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Testosterone Response in Older vs. Younger Men

© Copyright 2010 CorbisCorporationWhat role does a man’s age play with respect to his response to Testosterone therapy?

A group of researchers have studied incremental doses of testosterone on both older[1] and younger[2] men to compare the differences seen with Testosterone supplementation.
These studies measured many aspects of Testosterone supplementation both for each study group (Younger men and Older men). They also compared the results between the two groups in order to learn the similarities and differences.

Here is what they found…

Similarities

  • Muscle strength
  • Lean Body Mass

This is good news for both younger and older men wanting to make changes in their body composition. Specifically, it doesn’t matter what age you are, you will increase muscle strength, size and decrease percentage body fat. The researchers also learned that these changes increase with higher doses.

Differences

  • Older men achieve higher testosterone levels at the same dose when compared to younger men.
  • Side effect profiles were different for older men vs. younger men.

o Younger men tended to have more acne compared to older men

o Older men had higher elevations in red blood cell counts (hematocrit)

o Older men had a higher frequency of leg edema

o Older men had a higher frequency of prostate events

This study highlights the need for careful monitoring of Testosterone replacement by knowledgeable health care professionals. Changing one single variable such as age can effect how Testosterone replacement will effect your body.

While aging decreases the effectiveness of many systems in a man’s body, the good news is that his body will respond beneficially to testosterone replacement whatever his age.
Be well,

Amit

[1] Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle. (Link)

[2] Testosterone dose-response relationships in healthy young men. (Link)

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